2015考研英语阅读英文原刊《经济学人》：杀手在敲门

　　2015考研英语复习正是强化复习阶段，考研英语阅读在考研英语中占了40分，所以考研英语阅读是英语科目中重要的一项。新东方名师范猛老师曾建议过考研生需要坚持每天泛读10-15分钟的英文原刊。强烈推荐了杂志《经济学人》杂志中的文章也是考研英语的主要材料来源.希望考研考生认真阅读，快速提高考研英语阅读水平。

　　A killer in close up

　　杀手在敲门

　　You can do a lot of damage with just seven genes

　　七个基因，祸害无穷

　　EBOLA is a simple virus, but also a subtle one. Thestringy looking particles consist of a genomewrapped up in two layers of protein. This long, thinpackage, along with a large protein called apolymerase, is packed into a membrane that is studded with a glycoproteins—that is, proteinswith sugar stuck to them.

　　埃博拉病毒看似简单，实则精妙。由两层蛋白质包裹着由基因组组成的丝状体，形成长而薄的包膜，包膜上布满醣蛋白颗粒，所谓醣蛋白就是糖分子附着在蛋白质上。

　　When the virus infects a cell the polymerase makes copies of the genome and the cell istricked into using these to make the proteins that the virus needs. These include two, calledVP35 and VP24, which stymie interferons, a class of molecule that alerts the immune systemto infection. VP35 prevents interferons from being made; VP24 stops their cries for help frombeing heard. The sugars on the virus's outside make it hard for other parts of the immunesystem to get to grips with; to confuse things more, the virus makes infected cells producemore glycoprotein than it needs for its coat, with the surplus simply secreted into thebloodstream. Antibodies which would otherwise attack the virus stick to this decoy proteininstead.

　　当埃博拉病毒感染细胞时，病毒的聚合酶就复制基因组，并诱使细胞使用这些基因组制造病毒所需要的蛋白质。这种蛋白质有两种类型，分别叫做VP35和VP24，它们阻碍干扰素发挥作用，干扰素是一类能向免疫系统发出警示作用的细胞因子。VP35阻止细胞干扰素形成，VP24则阻碍免疫系统接受干扰素的警示信息。病毒外附着的糖分子阻止免疫系统的其他部分捕获该病毒;更麻烦的是，病毒使得被感染的细胞生成超过其表皮需要量的醣蛋白，于是，这些过剩的醣蛋白直接代谢入血液。于是，抗体只能附着在这些作为诱饵的醣蛋白上面，而不会攻击病毒。

　　Immune cells which the virus attacks in the bloodstream early on carry the infection to theliver, the spleen and lymph nodes. Symptoms may manifest themselves in a day or two ormay wait weeks (see chart). Eventually the virus's spread triggers an immune overreactionknown as a cytokine storm. Blood-vessel walls become leaky, blood pressure and coretemperature drop, organs fail and the body goes into shock. Various combinations of thoseand other symptoms kill about 70% of those who get ill.

　　血液中先前被病毒攻击的免疫细胞携带感染元进入肝脏、脾脏和淋巴结。症状可能会在1天、2天或者等上1周后显示出来。最后，病毒的传播引发了免疫过载，这称为“细胞素风暴”。于是，血管壁开始渗漏，血压和体核温度下降，导致器官衰竭，身体休克。这些作用结合其它症状使得70%的患者死亡。

　　Some of the sick weather the storm, but most who survive infection do so by never gettingto its direst straits. Some do not succumb at all: a study of people who had direct contact withpatients during outbreaks in Gabon in 1996 showed that some had definitely been infected, butnever fallen ill.

　　一些病人能挨过细胞素风暴，但是能在感染后活下来的人大多数靠的是没有遇到杀招，但有一类人根本就是命硬：一项针对1996年在加蓬爆发期间和病人直接接触的人群的研究表明：一些人绝对受到了感染，但从没有生病。翻译：沈竹 校对：徐牧之

文章来源：经济学人

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