四川大学生命科学学院研究生导师：王亚军

　　研究方向：

　　动物细胞生物学、繁殖生物学、比较内分泌学

　　项目支持：

　　国家自然科学基金、转基因生物新品种培育重大专项、国家高技术研究发展计划.

　　代表性论文：

　　1. Wang Y*, Wang CY, Wu Y, et al. Identification of the Receptors for Prolactin-releasing Peptide (PrRP) and Carassius RFamide Peptide (C-RFa) in Chickens. Endocrinology, 153: p1-14, 2012 (online) (*通讯作者) (IF=4.993).

　　2. Wang Y*, Huang G, Li J., et al., Characterization of Chicken Secretin (SCT) and Secretin Receptor (SCTR) Genes: A Novel Secretin-like Peptide (SCT-LP) and Secretin Encoded in a Single Gene. Molecular and Cellular Endocrinology, 348: 270-280, 2012 (*通迅作者) (IF=4.118).

　　3. Huang G, Li J, Fu H, Yan Z, Bu G, He X, Wang Y* Characterization of glucagon-like peptide 1 receptor (GLP1R) gene in chickens: functional analysis, tissue distribution, and identification of its transcript variants. Domestic Animal Endocrinology (online), p1-15, 2012 (* 通迅作者) (IF= 1.896)

　　4. Ho JC, Kwok AH, Zhao D, Wang Y*, et al. Characterization of the chicken galanin type I receptor (GalR1) and a novel GalR1-like receptor (GalR1-L). General and Comparative Endocrinology 170: 391-400, 2011 (*通讯作者) (IF=3.108).

　　5. Ruiqiang Li, Wei Fan, Geng Tian, Hongmei Zhu, Lin He, ……, Yajun Wang*… Lars Bolund, Karsten Kristiansen, Gane Ka-Shu Wong, Maynard Olson, Xiuqing Zhang, Songgang Li, Huanming Yang, Jian Wang & Jun Wang. The sequence and de novo assembly of the giant panda genome. Nature, 463: 311-317, 2010 (IF=36.101)

　　6. Wang Y*, Li J, Kwok AHY, et al., A novel prolactin-like protein (PRL-L) gene in chickens and zebrafish: Cloning and Characterization of its tissue expression. General and Comparative endocrinology 166: 200-210, 2010. (IF=3.108)

　　7. Wang Y*, Li J, C. Wang CY, et al., Characterization of the receptors for chicken GHRH and GHRH-related peptides: Identification of a novel receptor for GHRH and the receptor for GHRH-LP (PRP). Domestic Animal Endocrinology 38: 13-31, 2010 (IF=1.896).

　　8. Lynch VJ，Tanzer A, Wang Y*, et al., Adaptive changes in the transcription factor HoxA-11 are essential for the evolution of pregnancy in mammals. Proc. Natl. Acad. Sci. U S A. 105: 14925-14933, 2008. (IF=9.598)

　　9. Wang J, Wang Y*, Li X, et al., Cloning, tissues distribution and functional characterization of chicken glucagon receptor. Poultry science 87: 2678-2688, 2008 (IF=1.603)

　　10. Kwok AHY, Wang Y*, Wang CY, et al., Molecular cloning and characterization of chicken prostaglandin E receptor subtypes 2 and 4 (EP2 and EP4) General and Comparative Endocrinology, 157: 99-106, 2008 (IF=3.108)

　　11. Wang Y*, Li J, Wang CY, et al., Identification of the endogenous ligands for chicken growth hormone-releasing hormone (GHRH) receptor. Evidence for a separate gene encoding GHRH in submammalian vertebrates. Endocrinology 148: 2405-2416, 2007. (IF=5.045)

　　12. Wang Y*, Li J，Wang CY, et al., Epidermal growth factor receptor (EGFR) ligand in the chicken ovary: I) Evidence for heparin binding epidermal growth factor-like growth factor (HB-EGF) as a potential oocyte-derived factor to control granulosa cell proliferation and HB-EGF and Kit ligand expression. Endocrinology 148: 3426 – 3440, 2007 (IF=5.045).

　　13. Wang Y, Wang Z, Li J, Wang Y*, et al., A database for chicken full-length cDNAs. Physiological Genomics 28:141-5, 2007 (IF=3.368).

　　14. Kwok AHY, Wang Y*, Wang CY, et al., Cloning of chicken glucocorticoid receptor (GR) and characterization of its expression in pituitary and extra-pituitary tissues. Poultry Science 86: 423-430, 2007 (IF=1.603).

　　15. Wang CY*, Wang Y*, Kwok AHY et al., Identification of two novel chicken GHRH receptor splice variants: implications for the roles of aspartate 56 in the receptor activation and direct ligand receptor interaction. Journal of Endocrinology 195: 525-536, 2007 (IF=2.636) (同等贡献).

　　16. Wang CY, Wang Y*, Li J et al. Expression profiles of chicken growth hormone-releasing hormone (GHRH) and growth hormone-releasing hormone receptor (GHRHR) during chicken embryonic pituitary development. Poultry Science, 85: 569-576, 2006, (IF=1.603).

　　17. Kwok HF, So WK, Wang Y* et al, Zebrafish gonadotropins and their receptors: I. Cloning and characterization of zebrafish follicle-stimulating hormone and luteinizing hormone receptors: Evidence for their distinct functions in follicle development. Biology of Reproduction, 72: 1370-1381, 2005 (IF=3.670).

　　18. Wang Y* & Ge W Cloning of Epidermal growth factor (EGF) and EGF receptor from the zebrafish ovary: evidence for EGF as a potential paracrine factor from the oocyte to regulate activin/follistatin system in the follicle cells. Biology of Reproduction, 71: 749-760, 2004 (IF=3.670).

　　19. Wang Y* & Ge W. Developmental profiles of activin βA, βB, and follistatin expression in the zebrafish ovary: evidence for their differential roles during sexual maturation and ovulatory cycle. Biology of Reproduction, 71: 2056-2064, 2004 (IF=3.670).

　　20. Wang Y* & Ge W. Cloning of zebrafish ovarian P450c17 (CYP17,17α-hydroxylase/17,20-lyase) and characterization of its expression in gonadal and extra-gonadal tissues. General and Comparative Endocrinology, 135: 241-249, 2004 (IF=3.108)

　　21. Wang Y* & Ge W Involvement of cyclic adenosine 3’,5’-monophosphate in the differential regulation of activin βA and βB expression by gonadotropin in the zebrafish ovarian follicle cells. Endocrinology, 144: 491-499, 2003 (IF=5.045).

　　22. Wang Y*, Wong AOL & Ge W Cloning, regulation of mRNA expression and function of a new isoform of pituitary adenylate cyclase-activating polypeptide (PACAP) in the zebrafish ovary. Endocrinology, 144: 4799-4810, 2003 (IF=5.045).

　　23. Wang Y* & Ge W Spatial expression patterns of activin and its signaling system in the zebrafish ovarian follicle: Evidence for paracrine action of activin on the oocytes. Biology of Reproduction, 69: 1998-2006, 2003. (IF=3.670)

　　24. Wang Y* & Ge W (2003) Gonadotropin regulation of follistatin expression in the cultured ovarian follicle cells of zebrafish, Danio rerio. General and Comparative Endocrinology, 134: 308-315 (IF=3.108)

　　25. Wang Y* & Ge W. Cloning of zebrafish ovarian carbonyl reductase-like 20β-hydroxysteroid dehydrogenase and characterization of its spatial and temporal expression. General and Comparative Endocrinology, 127: 209-216, 2002 (IF=3.108).

　　会议报告

　　1) 王亚军 The 10th International Symposium on Avian Endocrinology 2012 (ISAE2012) (June 5-9, 2012, Japan).(大会报告, Invited speaker)Title: ‘Molecular characterization of the receptors for chicken GHRH, PrRP and their related peptides: An emerging evolutionary story’

　　获奖:

　　2003年度 “香港中文大学研究生最佳研究成绩奖”